The Alzheimers Gene: What Difference Does it Make?

Here is an interesting article on Alzheimer’s that I found and wanted to pass along to you.  For more assistance with an aging loved one in your life visit our website at www.caremanage.com

PHILADELPHIA – In the most comprehensive study to date, neurologists have clearly identified significant differences in the ways that Alzheimer’s disease (AD) affects patients with and without the apolipoprotein E ε4 gene (APOE ε4), a known genetic risk factor for the neurodegenerative disease, using a combination of cognitive and neuroanatomic measures. The study found that this gene influences the way the disease manifests, even at its mildest clinical stages.
Study highlights include:
·      Patients with mild AD who carry the ε4 form of the APOE gene perform more poorly on memory tests and have more prominent abnormalities in brain regions critical for memory, compared with patients without this gene variant.
·      In contrast, patients with mild AD who do not have the APOE ε4 gene perform more poorly on tests of attention, language, and executive function and have more prominent abnormalities in brain regions critical for these abilities, compared to patients with APOE ε4.
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Content Provided By www.AlzheimersWeekly.com

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